Status: Funded - Open
A smartphone-based biosensor for assessing iron status in children by detection of ferritin and sTfR
Balaji Srinivasan, PhD
BACKGROUND: The worldwide prevalence of anemia is 47% among preschool-age children due to iron deficiency as the primary cause, and if an accurate/early diagnosis is made, long-term sequelae can be prevented.
GAP: At present there’s a lack of portable point-of-care testing (POCT) technology to provide easily accessible diagnostic testing in a cost-effective manner for an early detection of ID in children, even in limited-resource settings, which in turn can improve the chances of a successful treatment.
HYPOTHESIS: Millions of children worldwide suffer from ID and the long-term consequences of ID in children can be prevented if an early diagnosis is made through a point-of-care, cost-effective, easily accessible, portable biosensor technology.
METHODS: This proposal is focused on technology development for a portable smartphone-based biosensor for assessing iron status in children by detection of ferritin/sTfR
IMPACT: Early detection of iron status and its periodic monitoring in children to study the effects of a corrective nutrition program can be challenging, especially in limited resource settings. The development of a portable, user-friendly, cost-effective and smartphone-based POCT will enable home-use test kits as well as testing in field and survey settings for iron deficiency possible.