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Currently Running Grants - E.W. "Al" Thrasher Awards

Since the Fund was established, over $70 million has been awarded for more than 650 projects. Following is a list of grants that are currently running.
Principal Investigator Supervising Institution Project Title
Cara B. Ebbeling, Ph.D. Children's Hospital Boston Low-glycemic load vs. low-fat diet for treating PCOS in obese adolescents
Aaron S. Kelly, Ph.D. University of Minnesota Medical School Vascular consequences of ADHD medication use in children and adolescents
Amit M. Mathur, MBBS, M.D. Washington University School of Medicine A study of the impact of sub clinical seizure treatment in term infants with neonatal encephalopathy
David A. Stevenson, M.D. University of Utah Effects of physical training on bone and muscle quality, muscle strength, and motor coordination in children with neurofibromatosis type 1
James M. Tielsch, Ph.D. Johns Hopkins University Impact of reducing carbon monoxide exposure from use of biomass fuel sources in the home on prematurity and intrauterine growth restriction in rural Southern Nepal: The Nepal Cookstove Intervention Trial
Carol L. Wagner, M.D. Medical University of South Carolina Three-year follow-up study of a vitamin D supplementation pregnancy cohort in South Carolina
Lifeng Yu, Ph.D. Mayo Clinic College of Medicine Radiation dose reduction with novel denoising techniques and lower X-ray tube energies for pediatric CT
Fernando P. Polack, M.D. Vanderbilt University Medical Center The role of human metapneumovirus infection in asthmatic exacerbations in pediatric patients
Ludo Max, Ph.D. University of Washington Neural maturation in children with persistent developmental stuttering: Electrophysiological studies of central auditory pathway activation from brain stem to cortex
Abdullah Baqui, MBBS, MPH, Dr.PH Johns Hopkins University The effect of antenatal vitamin D supplementation on maternal-fetal vitamin D status and neonatal immune function: a randomized controlled trial in Bangladesh
Thomas O. Carpenter, M.D. Yale University School of Medicine Assessing vitamin D requirements: the role of vitamin D binding protein on the biochemical and physiological responses to vitamin D supplementation in infants and toddlers
Glenn T. Furuta, M.D. University of Colorado Denver, School of Medicine Novel proteomic analysis of eosinophilic esophagitis
Christopher Semsarian, MBBS, Ph.D. Centenary Institute Prevention of sudden unexplained death in children in Australia
Frank T. Wieringa, M.D., Ph.D. IHD-Hanoi Making maternal post-partum vitamin A supplementation effective: The role of timing and inflammation
Michael E. Pichichero, M.D. Rochester General Hospital The changing epidemiology of pneumococcal otitis media
Kenneth H. Brown, M.D. University of California, Davis Community-based intervention trial to compare the impact of preventive and therapeutic zinc supplementation programs among young children in Burkina Faso
Eduard Gratacos, M.D., Ph.D. University of Barcelona Clinical use of assessing regional brain circulation perfusion to identify long term neurodevelopmental anomalies in small for gestational age fetuses (SGA)
Pamela J. Kling, M.D. University of Wisconsin-Madison Early screening and interventions for infants at-risk for iron deficiency
Jiong-Jiong Wang, Ph.D. University of Pennsylvania ASL perfusion MRI in pediatric brain tumor
Daniel K. Benjamin, Jr., M.D., MPH, Ph.D. Duke Clinical Research Institute Fluconazole prophylaxis for the prevention of candidiasis in neonates <750 grams birth weight
Christopher C. Giza, M.D. UCLA School of Medicine Early monitoring for seizures and long-term global outcomes following moderate to severe brain injury in children
Sheldon L. Kaplan, M.D. Texas Children's Hospital Randomized trial of bleach baths versus no bleach baths in the prevention of recurrent infections caused by community-acquired Staphylococcus aureus in children
Seema Kumar, M.D. Mayo Clinic College of Medicine Significance of vitamin D status in obese adolescents: A pilot study to examine the effect of vitamin D3 supplementation on insulin resistance and cardiovascular risk factors
John J. Lima, Pharm.D. Nemours Children's Clinic Effect of Gly16Arg polymorphism in ADRB2 gene on asthma control in children receiving long acting beta agonists
Jose Luis Millan, Ph.D. Burnham Institute for Medical Research Enzyme replacement therapy for infantile hypophosphatasia
Eric I. Felner, M.D. Emory University School of Medicine Insulin delivery using microneedles in type 1 diabetes
Ian Mackenzie, M.D. Liverpool School of Tropical Medicine Randomized trial of treatment of Chronic Suppurative Otitis Media (CSOM) in Kenyan children
Luke C. Mullany, Ph.D. Johns Hopkins University Bacterial colonization of the neonatal umbilical cord and impact of 4.0% chlorhexidine cleansing on bacteriological profile of the umbilical cord of newborns in Sylhet District, Bangladesh
Charles A. Nelson, III, Ph.D. Harvard Medical School Predicting neurocognitive outcome following perinatal hypoxic-ischemic injury
Scott A. Rivkees, M.D. Yale School of Medicine Identification and treatment of biological clock dysfunction in optic nerve hypoplasia
Patricia Zuk, Ph.D. UCLA School of Medicine Use of adipose-derived stem cells in the healing of cleft defects
Stefan Bluml, Ph.D. Children's Hospital Los Angeles Metabolic profiling of diffuse intrinsic brain stem glioma in pediatrics
Laura Gibson, M.D. UMass Medical School Cytomegalovirus (CMV)-specific cell-mediated immunity in infants with congenital CMV infection
K. Michael Hambidge, M.D., Sc.D. University of Colorado Denver Development and health of rural Chinese children fed meat as a daily complementary food from 6-18 months of age
Tor A. Strand, M.D., Ph.D. University of Bergen Supplementation of folic acid and vitamin B12 for prevention of childhood infections in young Indian children
Nicholas J. White, M.D. Mahidol University A post mortem study of fatal P. falciparum malaria in Mozambique
Yvonne Wu, M.D., MPH UCSF School of Medicine Phase I multicenter clinical trial of early high-dose erythropoietin in term infants with hypoxic-ischemic encephalopathy
Adekunle Dawodu, M.D. Cincinnati Children's Hospital Medical Ctr. High prevalence of rickets and subclinical maternal and childhood vitamin D deficiency in the Middle East: A randomized controlled trial of prenatal vitamin D supplementation to prevent vitamin D deficiency in mothers and their infants
Jennifer F. Friedman, M.D., Ph.D., MPH Brown University Infant hemoglobin, nutritional status and neuro-cognitive development following maternal treatment for S. japonicum during pregnancy
Wilfried Karmaus, M.D., MPH University of South Carolina The immune constituents and fatty acids in breast milk and their association with childhood infections and allergies
Michael A. Portman, M.D. Seattle Children's Role of FcGamma receptor polymorphisms in determining IVIG response in Kawasaki Disease
Michael R. Pranzatelli, M.D. Southern Illinois School of Medicine Cytokines as biomarkers and therapeutic targets in Paraneoplastic Opsoclonus-Myoclonus Syndrome (OMS)
Suzanne Schuh, M.D. The Hospital for Sick Children Impact of oximetry on disposition in acute bronchiolitis
Susan Wu, M.D. USC School of Medicine Nebulized hypertonic saline for treatment of viral bronchiolitis
Theoklis Zaoutis, M.D. The Children's Hospital of Philadelphia The impact of antibiotic prophylaxis on the development of antimicrobial resistance
Caroline J. Chantry, M.D. UC Davis Medical Center Feasibility and pilot efficacy of flash-heated breast milk for reduction of maternal-to-child transmission of HIV in Tanzania
Andrew M. Gordon, Ph.D. Teachers College, Columbia University Hand-Arm Bimanual Intensive Therapy (HABIT) in children with Cerebral Palsy
Anna M. Mandalakas, M.D. Case School of Medicine Diagnosis of tuberculosis infection in HIV co-infected children
David S. Millington, Ph.D. Duke University Medical Center Investigating the clinical variability of creatine pathway and molybdenum cofactor disorders
Fernando Sempertegui, M.D. Corporacion Ecuatoriana de Biotecnologia Effects of zinc as an adjunct to treatment of pneumonia in young children
Elizabeth A. Szalay, M.D. UNM School of Medicine Prevention of immobilization-induced osteoporosis in children
Richard H. Haas, M.D. UCSD School of Medicine Intravenous levetiracetam for the treatment of neonatal seizures: A pharmacokinetic and preliminary efficacy and safety study
Wei-Chiang Lin, Ph.D. Florida International University Optimizing pediatric brain tumor surgery through optical spectroscopy to enhance survival and quality of life
Alexandre E. Medina, Ph.D. Virginia Commonwealth University Restoring plasticity in fetal anticonvulsant syndrome using a phosphodiesterase inhibitor
William C. Mobley, M.D., Ph.D. Stanford University School of Medicine Targeting APP gene expression to improve and maintain cognition in children and adults with Down Syndrome
John A. Widness, M.D. University of Iowa College of Medicine Red blood cell recovery and survival following transfusion in infants
Luis E. Cuevas, M.D. Liverpool School of Tropical Medicine Towards new diagnostic approaches for active and latent TB infections using IFN-y assays in African children
Sherwin J. Isenberg, M.D. Harbor-UCLA Medical Center A clinical trial of the treatment of fungal corneal ulcers with povidone-iodine
Marcel Reyners, M.D. International Centre for Reproductive Health Impact of highly active anti retroviral therapy during pregnancy and breastfeeding on mother-to-child-transmission of HIV and mother's health: The Kesho Bora Study
Fernando P. Polack, M.D. Johns Hopkins School of Medicine The role of human metapneumovirus infection in asthmatic exacerbations in pediatric patients
Afzal A. Siddiqui, Ph.D. Texas Tech Health Sciences Center Schistosomiasis vaccine
Eduardo Villamor, M.D., Dr.PH Harvard School of Public Health Trial of zinc and HIV progression in children
Steven H. Abman, M.D. UCHSC Novel strategies for the prevention and treatment of chronic lung disease in premature newborns
Geoffrey P. Davidson, M.D. Children, Youth & Women's Health Service A new diagnostic standard for the assessment of swallowing disorders in children
Eileen J. Klein, M.D., MPH University of Washington School of Medicine Improving sedation of children undergoing procedures in the Emergency Department: Evaluation of different dosages and routes of administration of the sedative Midazolam
Evelyn A. Paysse, M.D. Baylor College of Medicine Photorefractive Keratectomy (PRK) for ametropia in children: A prospective study
Sriram Ramaswamy, M.D. Creighton University Bone mineral content and bone metabolism in adolescents on antipsychotic therapy
Dharmapuri Vidyasagar, M.D. University of Illinois Medical Center The effect of captopril on experimental meconium aspiration
Lydia Aguilar-Bryan, M.D., Ph.D. Pacific Northwest Diabetes Research Institute Molecular basis for hyperinsulinemic hypoglycemia and permanent diabetes in newborns and infants
Robin K. Ohls, M.D. UNM School of Medicine A randomized, masked, placebo controlled study to assess the safety and efficacy of darbepoetin alfa administered to preterm infants
Jeanette C. Ramer, M.D. Penn State College of Medicine Assessment and treatment of copper/zinc imbalance in children with autism
Carl L. Bose, M.D. UNC School of Medicine The role of inflammation in infant chronic lung disease and related outcomes
Johanna Goldfarb, M.D. Cleveland Clinic Children's Hospital Are the betaherpesviruses important pathogens in immunocompromised children?
Friedhelm Hildebrandt, M.D. University of Michigan Medical School Molecular genetics of focal-segmentalglomerulosclerosis (FSGS) in African American children: Mutational analysis and gene identification to establish diagnosis and response to treatment
Gail M. Seigel, Ph.D. SUNY at Buffalo School of Medicine Retinal autofluorescence as a diagnostic tool in Batten disease
Daniel K. Benjamin, Jr., M.D., MPH, Ph.D. Duke Clinical Research Institute Early diagnosis of neonatal candidiasis
Claudia B. Holzman, DVM, MPH, Ph.D. Michigan State University Assessing antenatal biomarkers of preterm delivery
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